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Follow the directions on the prescription label. Swallow the tablets with a drink of water. You may take tamoxifen with or without food. Take your doses at regular intervals. Do not stop taking except on your prescriber's advice.<br /> <br /> Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.<br /> <h3><u>What if I miss a dose?</u></h3><br /> If you miss a dose, take it as soon as you remember, and then take the next dose as usual. Do not take double or extra doses. If you vomit after taking a dose call your prescriber or health care professional for advice.<br /> <h3><u>What drug(s) may interact with tamoxifen?</u></h3><br /> • aminogluthemide<br /> • bosentan<br /> • bromocriptine<br /> • chemotherapy drugs<br /> • cyclosporine<br /> • delavirdine<br /> • dietary supplements like black cohosh, chasteberry, melatonin, or soy isoflavones<br /> • efavirenz<br /> • estrogen hormones, including some birth control products<br /> • nevirapine<br /> • protease inhibitors<br /> • rifampin<br /> • warfarin<br /> <br /> Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also, tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. 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You may need to have blood drawn to check your blood counts, calcium, and/or cholesterol. Serious side effects to tamoxifen occur rarely. However, you should contact your health care professional if you think you are having any problems with your tamoxifen therapy. Some side effects of tamoxifen may occur soon after starting the drug, but others may first appear at any time during your treatment.<br /> <br /> When you start taking tamoxifen to treat breast cancer, bone or tumor pain may increase. This means that tamoxifen is working and the pain should soon decrease. If the pain is severe, call your prescriber or health care professional. During this initial time, if you experience confusion or increased nausea, thirst, urination, or vomiting call your health care professional immediately.<br /> <br /> If you are taking tamoxifen to reduce your risk of getting breast cancer, you should know that tamoxifen does not prevent all types of breast cancer. You should have regular gynecological check-ups, including breast exams and mammograms, and follow your prescriber's recommendations. If breast cancer or other problem occurs, there is no guarantee that it will be detected at an early stage. This is why it is important to continue with regular check-ups. Women who are or have taken tamoxifen should inform their prescriber or health care professional of any irregular menstrual cycles, abnormal vaginal bleeding, changes in vaginal discharge, or pelvic pain or pressure.<br /> <br /> Women should not become pregnant while taking tamoxifen or for 2 months after tamoxifen therapy has stopped. You should see your prescriber immediately if you think you may have become pregnant while taking tamoxifen. Use of tamoxifen early in pregnancy may harm your unborn child. Women who can have children should use barrier birth control (condoms) or other methods of birth control that do not use hormones. Talk with your health care provider for birth control advice. Because tamoxifen may cause women to ovulate, it may increase the risk of getting pregnant if appropriate birth control is not used. <br /> <br /> Women who take tamoxifen are at increased risk for developing blood clots. Some women may develop more than one clot, even if tamoxifen is stopped. If you experience pain or swelling in your calves, sudden chest pain, shortness of breath, or coughing up blood, call your prescriber or health care professional right away. Tamoxifen may increase the chance of having a stroke. If you experience symptoms of a stroke such as weakness, difficulty walking or talking, or numbness, contact your prescriber immediately.<br /> <br /> Tamoxifen may cause cataracts or changes to parts of the eye known as the cornea or retina. 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